Monday, July 18, 2016

Supportive Treatment of Multiple Myeloma

Supportive Treatment of Multiple Myeloma Supportive treatment is the treatment that aim to treat the signs & symptoms or reduce them; it is not aim to treat the disease itself. Renal Impairment :- Rehydrate. Treat the underlying cause (e.g. hypercalcemia, hyperuricemia). Dialysis. Drink at least 3 Liter of fluid daily (all multiple myeloma cases). Bone disease and hypercalcemia :- Bisphosphonates (such as pamidronate,...

Sunday, July 17, 2016

Multiple Myeloma: An Overview

Normal 0 false false false MicrosoftInternetExplorer4 Multiple Myeloma: An Overview Definition:- Multiple myeloma (MM) is a malignant bone marrow–based, plasma cell neoplasm associated with abnormal protein production. Multiple myeloma also called...

Thursday, April 7, 2016

Hemophilia: An Overview

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Tuesday, December 22, 2015

The Role of 2,3-Diphophoglycerate

The Role of 2,3-Diphophoglycerate      The major function of the hemoglobin molecule is the transport of oxygen to the tissues. The oxygen affinity of the hemoglobin molecule is associated with the spatial rearrangement of the molecule and is regulated by the concentration of phosphates, particularly 2,3-DPG...

Friday, December 11, 2015

Alterations in Myeloid:Erythroid Ratio

           The M:E ratio is sensitive to hematologic factors that may impair red blood cell life span, inhibit overall production, or cause dramatic increases in a particular cell line. Each of these conditions reflects bone marrow dynamics through alterations of the M:E ratio. Many observations...

Bone Marrow & Myeloid:Erythroid Ratio

           The bone marrow is one of the largest organs of the body, encompassing 3% to 6% of body weight and weighing 1500 g in an adult. It is hard to conceptualize the bone marrow as an organ because it is not a solid organ that one can touch, measure, or weigh easily. Because bone marrow tissue...

Thursday, December 10, 2015

Iron Distribution

Iron-containing compounds in the body are one of two types: Functional compounds that serve in metabolic (hemoglobin, myoglobin, iron-responsive element-binding protein) or enzymatic (cytochromes, cytochrome oxygenase, catalase, peroxidase) functions Compounds that serve as transport (transferrin, transferrin receptor) or storage forms...
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