Saturday, November 28, 2015

Extramedullary Hematopoiesis

   
 


     Hematopoiesis in the bone marrow is called medullary hematopoiesis or intramedullary hematopoiesis.

   Blood cell production in hematopoietic tissue other than bone marrow is called extramedullary hematopoiesis.

   In certain hematologic disorders when hyperplasia of the marrow cannot meet the physiologic blood needs of the tissues, extramedullary hematopoiesis can occur in the hematopoietic organs that were active in the fetus, principally the liver and spleen. Organomegaly frequently accompanies significant hematopoietic activity at these sites. This extramedullary hematopoiesis in postnatal life reflects the ability of inert hematopoietic cells to become active, functional cells if the need arises.




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