Functions of the Spleen

Hematopoietic function:-

• Can produce white blood cells, red blood cells, and platelets if necessary.

Reservoir function:-

• One-third of platelets and granulocytes are stored in the spleen.

Filtration functions:-

• Aging red blood cells are destroyed.
• Spleen removes inclusion from red blood cells.
• If red blood cell membrane is less deformable or antibodycoated, spleen presents a hostile environment leading to production of spherocytes.

Immunologic function:-

• Opsonizing antibodies are produced, trapping and processing antigens from encapsulated organs.